![]() ![]() The mean CTFC in culprit arteries 90 minutes after thrombolytic administration followed a continuous unimodal distribution (there were not subpopulations of slow and fast flow) with a mean value of 39.2☒0.0 frames, which improved to 31.7☑2.9 frames by 18 to 36 hours ( P<.001). Therefore, the longer LAD frame counts were corrected by dividing by 1.7 to derive the corrected TIMI frame count (CTFC). In 78 consecutive normal arteries, the left anterior descending coronary artery (LAD) TIMI frame count (36.2☒.6 frames) was 1.7 times longer than the mean of the right coronary artery (20.4☓.0) and circumflex counts (22.2±4.1, P<.001 for either versus LAD). The TIMI frame-counting method was reproducible (mean absolute difference between two injections, 4.7☓.9 frames, n=85). Methods and Results In normal patients and patients with acute myocardial infarction (MI) (TIMI 4), the number of cineframes needed for dye to reach standardized distal landmarks was counted to objectively assess an index of coronary blood flow as a continuous variable. Customer Service and Ordering Informationīackground Although the Thrombolysis in Myocardial Infarction (TIMI) flow grade is a valuable and widely used qualitative measure in angiographic trials, it is limited by its subjective and categorical nature.Stroke: Vascular and Interventional Neurology. ![]() Journal of the American Heart Association (JAHA).Circ: Cardiovascular Quality & Outcomes.Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB). ![]()
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